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1

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

Zhong, Zhenyu, Umemura, Atsushi, Sanchez-Lopez, Elsa, Liang, Shuang, Shalapour, Shabnam, Wong, Jerry, He, Feng, Boassa, Daniela, Perkins, Guy, Ali, Syed Raza, McGeough, Matthew D., Ellisman, Mark H.,

Journal:

Year:

2016

Language:

english

File:

PDF, 5.95 MB

english, 2016

2

Identification of Liver Cancer Progenitors Whose Malignant Progression Depends on Autocrine IL-6 Signaling

He, Guobin, Dhar, Debanjan, Nakagawa, Hayato, Font-Burgada, Joan, Ogata, Hisanobu, Jiang, Yuhong, Shalapour, Shabnam, Seki, Ekihiro, Yost, Shawn E., Jepsen, Kristen, Frazer, Kelly A., Harismendy, Oliv

Journal:

Year:

2013

Language:

english

File:

PDF, 3.72 MB

english, 2013

3

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

Font-Burgada, Joan, Shalapour, Shabnam, Ramaswamy, Suvasini, Hsueh, Brian, Rossell, David, Umemura, Atsushi, Taniguchi, Koji, Nakagawa, Hayato, Valasek, Mark A., Ye, Li, Kopp, Janel L., Sander, Maike,

Journal:

Year:

2015

Language:

english

File:

PDF, 5.33 MB

english, 2015

4

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

Shalapour, Shabnam, Lin, Xue-Jia, Bastian, Ingmar N., Brain, John, Burt, Alastair D., Aksenov, Alexander A., Vrbanac, Alison F., Li, Weihua, Perkins, Andres, Matsutani, Takaji, Zhong, Zhenyu, Dhar, De

Journal:

Year:

2017

Language:

english

File:

PDF, 23.47 MB

english, 2017

5

Prenatal manifestation of pancytopenia in Pearson marrow-pancreas syndrome caused by a mitochondrial DNA deletion

Almut Giese, Renate Kirschner-Schwabe, Katharina Blumchen, Lena Wronski, Shabnam Shalapour, Javier Prada, Pablo Hernáiz Driever, Martin Brauer, Markus Schuelke, Günter Henze, Karl Seeger

Journal:

American Journal of Medical Genetics Part A

Year:

2007

Language:

english

File:

PDF, 167 KB

english, 2007

6

Commensal microflora and interferon-γ promote steady-state interleukin-7 production in vivo

Shabnam Shalapour, Katrin Deiser, Özen Sercan, Jan Tuckermann, Kerstin Minnich, Gerald Willimsky, Thomas Blankenstein, Günter J. Hämmerling, Bernd Arnold, Thomas Schüler

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 429 KB

english, 2010

7

Leukemia-associated genetic aberrations in mesenchymal stem cells of children with acute lymphoblastic leukemia

Shabnam Shalapour, Cornelia Eckert, Karl Seeger, Madlen Pfau, Javier Prada, Günter Henze, Thomas Blankenstein, Thomas Kammertoens

Journal:

Journal of Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 894 KB

english, 2010

8

The sequence of application of methotrexate and histone deacetylase inhibitors determines either a synergistic or an antagonistic response in childhood acute lymphoblastic leukemia cells

Bastian, L, Einsiedel, H G, Henze, G, Seeger, K, Shalapour, S

Journal:

Year:

2010

Language:

english

File:

PDF, 256 KB

english, 2010

9

Mutations and Deletions of the TP53 Gene Predict Nonresponse to Treatment and Poor Outcome in First Relapse of Childhood Acute Lymphoblastic Leukemia

Hof, J., Krentz, S., van Schewick, C., Korner, G., Shalapour, S., Rhein, P., Karawajew, L., Ludwig, W.-D., Seeger, K., Henze, G.

Journal:

Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 274 KB

english, 2011

10

The Serotonin Receptor-Antagonist Ondansetron Induces Significant Increases in the Expression of Interferon-Gamma Which Correlate with Antiproliferative Properties in the Acute Lymphoblastic Leukaemia Cell Line REH

Prada, J., Shalapour, S., Pfau, M., Henze, G., Seeger, K.

Journal:

Scandinavian Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 102 KB

english, 2012

11

Tissue injury and hypoxia promote malignant progression of prostate cancer by inducing CXCL13 expression in tumor myofibroblasts

Ammirante, M., Shalapour, S., Kang, Y., Jamieson, C. A. M., Karin, M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.75 MB

english, 2014

12

The immune response to sporadic colorectal cancer in a novel mouse model

Czéh, M, Loddenkemper, C, Shalapour, S, Schön, C, Robine, S, Goldscheid, E, Stein, H, Schüler, T, Willimsky, G, Blankenstein, T

Journal:

Year:

2010

Language:

english

File:

PDF, 1.35 MB

english, 2010

13

Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis

Wang, Kepeng, Kim, Min Kyoung, Di Caro, Giuseppe, Wong, Jerry, Shalapour, Shabnam, Wan, Jun, Zhang, Wei, Zhong, Zhenyu, Sanchez-Lopez, Elsa, Wu, Li-Wha, Taniguchi, Koji, Feng, Ying, Fearon, Eric, Griv

Journal:

Year:

2014

Language:

english

File:

PDF, 3.25 MB

english, 2014

14

Synergistic Activity of Bortezomib and HDACi in Preclinical Models of B-cell Precursor Acute Lymphoblastic Leukemia via Modulation of p53, PI3K/AKT, and NF- B

Bastian, L., Hof, J., Pfau, M., Fichtner, I., Eckert, C., Henze, G., Prada, J., von Stackelberg, A., Seeger, K., Shalapour, S.

Journal:

Clinical Cancer Research

Year:

2013

Language:

english

File:

PDF, 1.29 MB

english, 2013

15

The Thalidomide Analogue, CC-4047, Induces Apoptosis Signaling and Growth Arrest in Childhood Acute Lymphoblastic Leukemia Cells In vitro and In vivo

Shalapour, S., Zelmer, A., Pfau, M., Moderegger, E., Costa-Blechschmidt, C., van Landeghem, F. K. H., Taube, T., Fichtner, I., Buhrer, C., Henze, G., Seeger, K., Wellmann, S.

Journal:

Clinical Cancer Research

Year:

2006

Language:

english

File:

PDF, 437 KB

english, 2006

16

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy

Shalapour, Shabnam, Font-Burgada, Joan, Di Caro, Giuseppe, Zhong, Zhenyu, Sanchez-Lopez, Elsa, Dhar, Debanjan, Willimsky, Gerald, Ammirante, Massimo, Strasner, Amy, Hansel, Donna E., Jamieson, Christi

Journal:

Year:

2015

Language:

english

File:

PDF, 14.21 MB

english, 2015

17

An IKK -E2F1-BMI1 cascade activated by infiltrating B cells controls prostate regeneration and tumor recurrence

Ammirante, M., Kuraishy, A. I., Shalapour, S., Strasner, A., Ramirez-Sanchez, C., Zhang, W., Shabaik, A., Karin, M.

Journal:

Genes & Development

Year:

2013

Language:

english

File:

PDF, 761 KB

english, 2013

18

Antiproliferative effect of the serotonin receptor antagonist ondansetron in the acute lymphoblastic leukemia cell line REH

Prada, Javier, Shalapour, Shabnam, Pfau, Madlen, Henze, Guenter, Seeger, Karl

Journal:

Acta Oncologica

Year:

2011

Language:

english

File:

PDF, 120 KB

english, 2011

19

Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling

Sanchez-Lopez, E, Flashner-Abramson, E, Shalapour, S, Zhong, Z, Taniguchi, K, Levitzki, A, Karin, M

Journal:

Year:

2015

Language:

english

File:

PDF, 3.20 MB

english, 2015

20

Fatty Acid-Induced T Cell Loss Greases Liver Carcinogenesis

Shalapour, Shabnam, Karin, Michael

Journal:

Cell Metabolism

Year:

2016

Language:

english

File:

PDF, 490 KB

english, 2016

21

High VLA-4 expression is associated with adverse outcome and distinct gene expression changes in childhood B-cell precursor acute lymphoblastic leukemia at first relapse

Shalapour, S., Hof, J., Kirschner-Schwabe, R., Bastian, L., Eckert, C., Prada, J., Henze, G., von Stackelberg, A., Seeger, K.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

22

Erratum: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

Shalapour, Shabnam, Lin, Xue-Jia, Bastian, Ingmar N., Brain, John, Burt, Alastair D., Aksenov, Alexander A., Vrbanac, Alison F., Li, Weihua, Perkins, Andres, Matsutani, Takaji, Zhong, Zhenyu, Dhar, De

Journal:

Year:

2017

File:

PDF, 42 KB

2017

23

Antiproliferative Properties of the Serotonin Receptor Antagonist Ondansetron Correlate with Increased Nitric Oxides Release and Inducible Nitric Oxide Synthase Activity in the Acute Lymphoblastic Leukemia Cell Line REH

Prada, J., Shalapour, S., Pfau, M., Henze, G., Seeger, K.

Journal:

European Journal of Inflammation

Year:

2012

Language:

english

File:

PDF, 810 KB

english, 2012

24

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

Dhar, Debanjan, Antonucci, Laura, Nakagawa, Hayato, Kim, Ju Youn, Glitzner, Elisabeth, Caruso, Stefano, Shalapour, Shabnam, Yang, Ling, Valasek, Mark A., Lee, Sooyeon, Minnich, Kerstin, Seki, Ekihiro,

Journal:

Year:

2018

Language:

english

File:

PDF, 11.66 MB

english, 2018

25

Author Correction: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

Shalapour, Shabnam, Lin, Xue-Jia, Bastian, Ingmar N., Brain, John, Burt, Alastair D., Aksenov, Alexander A., Vrbanac, Alison F., Li, Weihua, Perkins, Andres, Matsutani, Takaji, Zhong, Zhenyu, Dhar, De

Journal:

Year:

2018

Language:

english

File:

PDF, 543 KB

english, 2018

26

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

Zhong, Zhenyu, Liang, Shuang, Sanchez-Lopez, Elsa, He, Feng, Shalapour, Shabnam, Lin, Xue-jia, Wong, Jerry, Ding, Siyuan, Seki, Ekihiro, Schnabl, Bernd, Hevener, Andrea L., Greenberg, Harry B., Kissel

Journal:

Year:

2018

Language:

english

File:

PDF, 35.02 MB

english, 2018

27

Integrative genomic analysis of mouse and human hepatocellular carcinoma

Dow, Michelle, Pyke, Rachel M., Tsui, Brian Y., Alexandrov, Ludmil B., Nakagawa, Hayato, Taniguchi, Koji, Seki, Ekihiro, Harismendy, Olivier, Shalapour, Shabnam, Karin, Michael, Carter, Hannah, Font-B

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

28

Immunity, inflammation, and cancer: an eternal fight between good and evil

Shalapour, Shabnam, Karin, Michael

Journal:

Journal of Clinical Investigation

Year:

2015

Language:

english

File:

PDF, 933 KB

english, 2015

29

Preclinical Models for Studying NASH-Driven HCC: How Useful Are They?

Febbraio, Mark A., Reibe, Saskia, Shalapour, Shabnam, Ooi, Geraldine J., Watt, Matthew J., Karin, Michael

Journal:

Cell Metabolism

Year:

2018

Language:

english

File:

PDF, 1.15 MB

english, 2018

30

Pas de Deux: Control of Anti-tumor Immunity by Cancer-Associated Inflammation

Shalapour, Shabnam, Karin, Michael

Journal:

Year:

2019

Language:

english

File:

PDF, 2.67 MB

english, 2019

31

Cruel to Be Kind: Epithelial, Microbial, and Immune Cell Interactions in Gastrointestinal Cancers

Shalapour, Shabnam, Karin, Michael

Journal:

Annual Review of Immunology

Year:

2020

File:

PDF, 13.05 MB

2020

32

Immunotherapy, Inflammation and Colorectal Cancer

Lichtenstern, Charles Robert, Ngu, Rachael Katie, Shalapour, Shabnam, Karin, Michael

Journal:

Year:

2020

File:

PDF, 976 KB

2020

33

Neoadjuvant rituximab modulates the tumor immune environment in patients with high risk prostate cancer

Ryan, Stephen T., Zhang, Jing, Burner, Danielle N., Liss, Michael, Pittman, Emily, Muldong, Michelle, Shabaik, Ahmed, Woo, Jason, Basler, Nicole, Cunha, Jonathan, Shalapour, Shabnam, Estrada, Monica V

Journal:

Journal of Translational Medicine

Year:

2020

File:

PDF, 1.62 MB

2020

34

Fructose stimulated de novo lipogenesis is promoted by inflammation

Todoric, Jelena, Di Caro, Giuseppe, Reibe, Saskia, Henstridge, Darren C., Green, Courtney R., Vrbanac, Alison, Ceteci, Fatih, Conche, Claire, McNulty, Reginald, Shalapour, Shabnam, Taniguchi, Koji, Me

Journal:

Nature Metabolism

Year:

2020

File:

PDF, 26.58 MB

2020